First, ensure you have the latest pika-patched mesa-git packages installed:
pikman upgrade
pikman install mesa-git mesa-git:i386
sudo reboot
fsr4_on %command%
Some supported games will show the FSR version as shown in the screenshot from Monster Hunter Wilds below, while others won't display this information.
The FSR 4 overrides require the game to already supports FSR 3.1.
If your game doesn't natively support FSR 3.1, you can use OptiScaler:
fsr4_on
launch command as described above